Translocation Mongolism Arising de Novo?

A de novo Reciprocal X; 9 Translocation in A Patient with Premature Ovarian Failure

A Rare Case of Acute Myeloid Leukemia with Translocation (3:3) Presenting with Features of Chronic Myelomonocytic Leukemia

Background: Acute Myeloid Leukemia (AML) with translocation (3,3) is a form of AML that may present de novo or may arise from a previous myelodysplastic syndrome. It is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. A subset of patients present with hepatosplenomegaly while a few cases h...

De-Novo Presentation of Histoid Leprosy on an Unusual Site

Histoid Leprosy (HL) is a rare variant of Lepromatous Leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. Patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. Here we report an unusual case of de novo (without any history of prior anti-leprotic therapy) ...

Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15).

We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46,XX (50) and the karyotype from skin fibroblasts is 46,XX (28)/46,XX,der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discus...

Culture of Waterbag Cells and Detection of Mangleism with G/D Adhesion in Trimester Embryos

A case mongolism due to "hereditary trans­location ·· is presented and discussed. The mother of the patient showed a Karyogram with 45-XX and G/D translocation. She had no stigmata. She had an abortio when she was 19 years old.  In the second pregnancy the amniotic fluid was gained by amniocentesis. The Karyogram showed G/D translocation mongolism. The Karyo­gram of the child's father was norm...